50664 INFANTILE PARALYSIS POLIO DEVELOPMENT OF POLIOMYELITIS VACCINE

This historic film “Unconditional Surrender” dates to the mid-1950s and was funded by the National Foundation for Infantile Paralysis / March of Dimes to promote the newly-developed poliomyelitis vaccine. The film shows Randy Kerr, the first boy to receive the Salk Vaccine. As the film shows, the Salk Vaccine was both safe and effective and went into commercial manufacture. The film does not mention Dr. Albert Sabin, whose oral vaccine came into use in 1961, so presumably the film dates from between 1956-1961.

The film shows the production of the vaccine, using the live virus, in a laboratory at Eli Lilly & Company. The film also shows how monkeys were used (3:14) as part of the development protocol. At 9:31, the National Institutes of Health are seen. Dr. Leonard Healy speaks about the results of the vaccination campaign at 12:20. The film also shows David Eisenhower, the grandson of President Eisenhower, who received the vaccine as a youngster.

The first polio vaccine was the inactivated polio vaccine. It was developed by Jonas Salk and came into use in 1955. The oral polio vaccine was developed by Albert Sabin and came into commercial use in 1961. They are on the World Health Organization’s List of Essential Medicines, the most important medication needed in a basic health system.The wholesale cost in the developing world is about 0.25 USD per dose for the oral form as of 2014. In the United States it costs between 25 and 50 USD for the inactivated form.

Polio vaccines are vaccines used to prevent poliomyelitis (polio). One type uses inactivated poliovirus and is given by injection (IPV), while the other type uses weakened poliovirus and is given by mouth (OPV). The World Health Organization recommends all children be vaccinated against polio. The two vaccines have eliminated polio from most of the world, and reduced the number of cases each year from an estimated 350,000 in 1988 to 74 in 2015.[

The inactivated polio vaccines are very safe. Mild redness or pain may occur at the site of injection. Oral polio vaccines result in vaccine-associated paralytic poliomyelitis in about three per million doses. This compares with one in two hundred who are paralysed following a polio infection. Both are generally safe to give during pregnancy and in those who have HIV/AIDS but are otherwise well.

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This film is part of the Periscope Film LLC archive, one of the largest historic military, transportation, and aviation stock footage collections in the USA. Entirely film backed, this material is available for licensing in 24p HD, 2k and 4k. For more information visit http://www.PeriscopeFilm.com

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